NORTH BRUNSWICK, N.J., October 29, 2021 (GLOBE NEWSWIRE) — BioAegis Therapeutics Inc., a clinical stage, private company developing therapies for infectious, inflammatory, and degenerative diseases based on a portfolio built around gelsolin technology, announces that it was selected to present at the MACRO Trends Investor Conference on November 12, 2021. Co-founders Valerie Ceva, COO, and Steven Cordovano, Vice President of Investor Relations, will present “Conquering Pneumonia and Systemic Inflammation with a Human Protein,” and highlight gelsolin, BioAegis’ novel host-directed treatment.
Conquering Pneumonia and Systemic Inflammation with a Human Protein
Supplementing human gelsolin with a recombinant form is a host-directed approach to treating inflammatory and infectious diseases. Gelsolin, a naturally occurring human protein that is abundant in healthy individuals, is a key component of the body’s innate immune system. It is a ‘master regulator of inflammation’. In the case of severe injury or infection, the body’s supply of gelsolin becomes depleted, which can lead to an overexuberant inflammatory response, organ damage, and death, as seen in COVID-19 and other conditions. Supplementing depleted systemic levels of gelsolin has enormous potential to prevent debilitating and potentially lethal ravages of inflammation, without suppressing the immune response to infection or the body’s ability to repair. Most current anti-inflammatory products, like steroids, work by suppressing immune function, putting patients at risk for subsequent infections and adverse events.
Pneumonia is a leading cause of death in the US and around the world. The adverse outcomes, including organ failure and mortality, generate an enormous financial burden on the health care system. As a result of organ damage, survivors often require ongoing care after being discharged from the ICU due to lingering neurocognitive and functional disabilities. Plasma gelsolin repletion therapy is expected to reduce these adverse outcomes as well as the costs associated with severe disease.
About MACRO Trends
MACRO Trends is a Dutch Investment advisory firm centered around a regularly published magazine edited by Brecht Arnaert, a monetary expert at the Rey Juan Carlos University in Madrid and has been the editor-in-chief of MACRO Trends since November 2013. The magazine covers a wide range of topics including the outlook for international currencies, gold, crypto currencies and special situation equities. It sponsors several research-focused conferences per year attended by a diverse group of European investors.
BioAegis Is Developing Gelsolin to Disrupt the Course of Inflammatory Diseases
BioAegis Therapeutics Inc. is a NJ-based clinical stage, private company whose mission is to capitalize on a key component of the body’s innate immune system, gelsolin, to prevent adverse outcomes in diseases driven by inflammation and infection. With the ability to replete gelsolin depleted by disease, BioAegis is in a unique position to deliver therapeutics that have the potential to disrupt the way many diseases are treated today.
BioAegis has the exclusive license to broad, worldwide intellectual property through Harvard-Brigham and Women’s Hospital. It holds over 40 patents issued for coverage of infection, inflammatory disease, renal failure, multiple sclerosis, and other neurologic diseases. BioAegis will also have US biologics exclusivity and has recently filed new IP in areas of unmet need.
This press release contains express or implied forward-looking statements, which are based on current expectations of management. These statements relate to, among other things, our expectations regarding management’s plans, objectives, and strategies. These statements are neither promises nor guarantees but are subject to a variety of risks and uncertainties, many of which are beyond our control, and which could cause actual results to differ materially from those contemplated in these forward-looking statements. BioAegis assumes no obligation to update any forward-looking statements appearing in this press release in the event of changing circumstances or otherwise, and such statements are current only as of the date they are made.