Publications of Interest
Recombinant Human Plasma Gelsolin (rhu-pGSN) in a Patient Hospitalized with Critical COVID-19 Pneumonia
Catteeuw JV, DiNubile MJ. Clin Infect Pract. 2021 Nov;12:100088. doi: 10.1016/j.clinpr.2021.100088. Epub 2021 Aug 10. PMID: 34396087; PMCID: PMC8353968.
Inflammatory Responses to Acute Carbon Monoxide Poisoning and the Role of Plasma Gelsolin.
Arya AK, Sethuraman K, Waddell J, Cha YS, Liang Y, Bhopale VM, Bhat AR, Imtiyaz Z, Dakessian A, Lee Y, Thom SR. Science Advances. 2025 Feb 7;11(6):eado9751. doi: 10.1126/sciadv.ado9751. Epub 2025 Feb 7. PMID: 39919185; PMCID: PMC11804920.
Gelsolin Alleviates Rheumatoid Arthritis by Negatively Regulating NLRP3 Inflammasome Activation
Lee J, Sasaki F, Koike E, Cho M, Lee Y, Dho SH, Lee J, Lee E, Toyohara E, Sunakawa M, Ishibashi M, Hung HH, Nishioka S, Komine R, Okura C, Shimizu M, Ikawa M, Yoshimura A, Morita R, Kim LK. Cell Death Differ. 2024 Dec;31(12):1679-1694. doi: 10.1038/s41418-024-01367-6. Epub 2024 Aug 24. PMID: 39179640; PMCID: PMC11618363.
Plasma Gelsolin Levels are Associated with Diabetes, Sex, Race, and Poverty
Hooten, Nicole Noren, et al. Journal of Translational Medicine, 10 Mar 2023
Proteomic Analysis Identifies Three Reliable Biomarkers of Intestinal Inflammation in the Stools of Patients With Inflammatory Bowel Disease
Vitali R, Palone F, Armuzzi A, Fulci V, Negroni A, Carissimi C, Cucchiara S, Stronati L. Journal of Crohn’s and Colitis. 2023 Jan 27;17(1):92-102. doi: 10.1093/ecco-jcc/jjac110. PMID: 36040453.
Blood-Borne Microparticles are an Inflammatory Stimulus in Type 2 Diabetes Mellitus
Thom, SR, et al. ImmunoHorizons, 1 Jan 2023
Adjunctive Recombinant Human Plasma Gelsolin for Severe Coronavirus Disease 2019 Pneumonia
DiNubile, Mark J, et al. Open Forum Infectious Dieases, 25 July 2022.
Gelsolin as a Potential Biomarker for Endoscopic Activity and Mucosal Healing in Ulcerative Colitis
Maeda K, Nakamura M, Yamamura T, Sawada T, Ishikawa E, Oishi A, Ikegami S, Kakushima N, Furukawa K, Iida T, Mizutani Y, Ishikawa T, Ohno E, Honda T, Ishigami M, Kawashima H. Biomedicines. 2022 Apr 9;10(4):872. doi: 10.3390/biomedicines10040872. PMID: 35453622; PMCID: PMC9029534.
Quorum Sensing by Gelsolin Regulates Programmed Cell Death 4 Expression and a Density-Dependent Phenotype in Macrophages
Reshma Kumari Sharma, et al. Journal of Immunology, 06 August 2021.
Plasma Gelsolin Modulates the Production and Fate of IL-1β-Containing Microparticles Following High-Pressure Exposure and Decompression
Bhopale, Veena M., et al. Journal of Applied Physiology, 25 March 2021.
An Immune-Based Biomarker Signature is Associated with Mortality in COVID-19 Patients
Abers, Michael S., et al. JCI Insight, 24 November 2020.
Low Plasma Gelsolin Concentrations in Chronic Granulomatous Disease
Audley J, Gliniewicz EF, Zarember KA, Hong HS, Wald G, Kuhns DB, Kang E, Malech HL, Suffredini AF, Noveck RJ, Dinubile MJ, Levinson SL, Stossel TP, Gallin JI. Inflammation. 2021 Feb;44(1):270-277. doi: 10.1007/s10753-020-01330-w. Epub 2020 Sep 4. PMID: 32886268; PMCID: PMC10825630.
Recombinant Human Plasma Gelsolin Improves Survival and Attenuates Lung Injury in a Murine Model of Multidrug-Resistant Pseudomonas Aeruginosa Pneumonia.
DiNubile, Mark J, et al. Open Forum Infectious Disease, 19 June 2020.
Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection
Messner, Christoph B., et al. Cell Systems, Cell Press, 2 June 2020.
Recombinant Human Plasma Gelsolin Stimulates Phagocytosis While Diminishing Excessive Inflammatory Responses in Mice with Pseudomonas Aeruginosa Sepsis.
Piktel, E., et al. Int. J. Mol. Sci., 4 April 2020