Plasma Gelsolin: Indicator of Inflammation and Its Potential as a Diagnostic Tool and Therapeutic Target
Piktel, Ewelina, et al. International Journal of Molecular Sciences, 25 August 2018
Free Actin Impairs Macrophage Bacterial Defenses via Scavenger Receptor MARCO Interaction With Reversal by Plasma Gelsolin
Ordija, Christine M, et al. American Journal of Physiology. Lung Cellular and Molecular Physiology, American Physiological Society, 1 June 2017.
Community-Acquired Pneumonia Requiring Hospitalization Among U.S. Adults
Jain, Seema, et al. The New England Journal of Medicine, U.S. National Library of Medicine, 30 July 2015.
Community-Acquired Pneumonia Requiring Hospitalization Among U.S. Adults Read More »
July 1, 2015: BioAegis Therapeutics Collaboration with Harvard School of Public Health Discovers Plasma Gelsolin Boosts the Immune Response to Pathogens
Dr. Lester Kobzik, Professor of Medicine, Harvard T.H. Chan School of Public Health Publishes: Plasma gelsolin improves lung host defense against pneumonia by enhancing macrophage NOS3 function. This major plasma gelsolin advancement was published in May in Journal of American Physiology—Lung, Cellular and Molecular Physiology. Read article here.
Plasma Gelsolin Improves Lung Host Defense Against Pneumonia by Enhancing Macrophage NOS3 Function
Yang, Zhiping, et al. American Journal of Physiology. Lung Cellular and Molecular Physiology, American Physiological Society, 1 July 2015.
April 15, 2015: BioAegis Therapeutics Completes Initial $8 Million Convertible Note: Round Oversubscribed
Company Enters into Collaborative Research Agreement with NIAID and Company to Run Phase 2a/b Trials in EU BioAegis Therapeutics Inc., a privately held biotechnology company commercializing plasma gelsolin (pGSN), an endogenous human protein that simultaneously modulates inflammation and boosts immune function announced that its recently closed convertible note round was oversubscribed by investors. Read article
The Value of Decreased Plasma Gelsolin Levels in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis in Diagnosis and Disease Activity Evaluation
Li, H, et al. SAGE Journals, 11 October 2013.
Reduction of Plasma Gelsolin Levels Correlates with Development of Multiple Organ Dysfunction Syndrome and Fatal Outcome in Burn Patients
Li-feng Huang, Yong-ming Yao, et al. PLOS ONE, Public Library of Science. 1 November, 2011
Plasma Gelsolin and Circulating Actin Correlate with Hemodialysis Mortality.
Lee, Po-Shun, et al. Journal of the American Society of Nephrology : JASN, American Society of Nephrology, May 2009.
Plasma Gelsolin and Circulating Actin Correlate with Hemodialysis Mortality. Read More »
Extracellular Gelsolin Binds Lipoteichoic Acid and Modulates Cellular Response to Proinflammatory Bacterial Wall Components
Bucki, Robert, et al. Journal of Immunology (Baltimore, Md. : 1950), U.S. National Library of Medicine, 1 Oct. 2008.