Extracellular gelsolin binds lipoteichoic acid and modulates cellular response to proinflammatory bacterial wall components.
Bucki R1, Byfield FJ, Kulakowska A, McCormick ME, Drozdowski W, Namiot Z, Hartung T, Janmey PA.October 1, 2008 Abstract The various functions of gelsolin in extracellular compartments are not yet clearly defined but include actin scavenging and antiinflammatory effects. Gelsolin was recently reported to bind endotoxin (LPS) from various Gram-negative bacteria with high affinity. In this study we investigate whether gelsolin also …
